PROTAC K-Ras Degrader-6
PROTAC K-Ras Degrader-6 is a PROTAC degrader targeting K-Ras that recruits KRas for ubiquitination and proteasomal degradation. PROTAC K-Ras Degrader-6 binds to cereblon, thereby ubiquitinating KRas. PROTAC K-Ras Degrader-6 can be used in cancer research.
(Pink: K-RAS ligand (HY-168671); Blue: Cereblon E3 ligase ligand; Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3052745-46-4
- Formula: C57H65F2N11O5
- Molecular Weight:1022.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3052745-46-4
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Molecular Weight 1022.19
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Formula C57H65F2N11O5
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SMILES
C#CC1=C(C=CC2=CC(O)=CC(C3=NC=C4C(N5CC6CCC(N6)C5)=NC(OCCN7CCC(CC7)CC8CCN(CC8)CC9CCN(CC9)C%10=CC%11=C(N(C(N%11C)=O)C%12CCC(NC%12=O)=O)C=C%10)=NC4=C3F)=C21)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)