3068205-08-0
Chemical Structure
KAT6A/B-IN-1
- CAS No.: 3068205-08-0
- Formula:C22H22N4O7S
- Molecular Weight:486.50
InChIKey: PISGFNODXGJANR-UHFFFAOYSA-N
SMILES: COC1=CC=C(OCCCO2)C2=C1S(NC3=NOC4=CC(CN5N=CC=C5)=CC(OC)=C34)(=O)=O
Biological Activity: KAT6A/B-IN-1 is a KAT6A/KAT6B inhibitor (IC50 = 3.2 nM and 25.2 nM) that inhibits lysine acetyltransferase activity. KAT6A/B-IN-1 inhibits cancer cell proliferation and tumor growth in xenograft models. KAT6A/B-IN-1 exhibits chemical and physical stability, low hygroscopicity, and reduced sensitivity to heat, humidity, and light. KAT6A/B-IN-1 is used in the study of breast cancer[1].
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KAT6A/B-IN-1 | KAT6A/B-IN-1 is a KAT6A/KAT6B inhibitor (IC50 = 3.2 nM and 25.2 nM) that inhibits lysine acetyltransferase activity. KAT6A/B-IN-1 inhibits cancer cell proliferation and tumor growth in xenograft models. KAT6A/B-IN-1 exhibits chemical and physical stability, low hygroscopicity, and reduced sensitivity to heat, humidity, and light. KAT6A/B-IN-1 is used in the study of breast cancer. | |||||||||||||||||||||
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