3077971-51-5
Chemical Structure
CRBN ligand-912
- CAS No.: 3077971-51-5
- Formula:C24H26N4O5
- Molecular Weight:450.49
InChIKey: DDDMRAMTLVIHRA-IBGZPJMESA-N
SMILES: O=C([C@@H](N1NC2=C(C=CC=C2OCC3=CC=C(CN4CCOCC4)C=C3)C1=O)CC5)NC5=O
Biological Activity: CRBN ligand-912 (Compound D1) is a molecular glue. CRBN ligand-912 targets CRBN, the substrate receptor of the cullin-RING E3 ubiquitin ligase complex, and modulates ubiquitin-proteasome-mediated protein degradation[1].
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CRBN ligand-912 | CRBN ligand-912 (Compound D1) is a molecular glue. CRBN ligand-912 targets CRBN, the substrate receptor of the cullin-RING E3 ubiquitin ligase complex, and modulates ubiquitin-proteasome-mediated protein degradation. | |||||||||||||||||||||
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