3097805-27-8
Chemical Structure
Antiviral agent-88
- CAS No.: 3097805-27-8
- Formula:C27H29F3N4O3
- Molecular Weight:514.54
InChIKey: OTGAIKWUPNMQKP-WOJBJXKFSA-N
SMILES: FC(F)(C1=C(C=CC(NC(C2=CN=C(C(N3[C@]4([H])C[C@](OC4)([H])C3)=O)C=C2)=O)=C1)N5CCC6(CCC6)CC5)F
Biological Activity: Antiviral agent-88 is a broad-spectrum Filovirus inhibitor. Antiviral agent-88 inhibits pEBOV, pMARV, Zaire, Sudan, Bundibugyo, Reston, and Tai Forest viruses with EC50 values of 0.23, 3.89, 0.23, 1.61, 1.19, 0.26, and 0.13 μM, respectively. Antiviral agent-88 blocks viral entry into host cells by binding to the viral glycoprotein and occupying its binding pocket. Antiviral agent-88 can be used in research on Ebola virus (EBOV) and Marburg virus (MARV) infections[1].
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Antiviral agent-88 | Antiviral agent-88 is a broad-spectrum Filovirus inhibitor. Antiviral agent-88 inhibits pEBOV, pMARV, Zaire, Sudan, Bundibugyo, Reston, and Tai Forest viruses with EC50 values of 0.23, 3.89, 0.23, 1.61, 1.19, 0.26, and 0.13 μM, respectively. Antiviral agent-88 blocks viral entry into host cells by binding to the viral glycoprotein and occupying its binding pocket. Antiviral agent-88 can be used in research on Ebola virus (EBOV) and Marburg virus (MARV) infections. | |||||||||||||||||||||
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