3111610-68-2
3111610-68-2
Chemical Structure
(M)-AVI-4773
- CAS No.: 3111610-68-2
- Formula:C23H14F2N6O2
- Molecular Weight:444.39
InChIKey: AUHVEXNDGPHSKX-UHFFFAOYSA-N
SMILES: FC1=CC(N=N2)=C(C=C1F)N2C3=C(C)N(CC#C)C(N(C4=CN=CC5=C4C=CC=C5)C3=O)=O
Biological Activity: (M)-AVI-4773 is an orally active, blood-brain barrier permeable coronaviruses MPro inhibitor with an IC50 of 2.5 nM aginst SARS-CoV-2 MPro. (M)-AVI-4773 produces a rapid onset antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection[1].
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(M)-AVI-4773 | (M)-AVI-4773 is an orally active, blood-brain barrier permeable coronaviruses MPro inhibitor with an IC50 of 2.5 nM aginst SARS-CoV-2 MPro. (M)-AVI-4773 produces a rapid onset antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection. | |||||||||||||||||||||
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