3133348-60-1
3133348-60-1
Chemical Structure
CYP51-IN-33
- CAS No.: 3133348-60-1
- Formula:C14H12Cl2N4OS
- Molecular Weight:355.24
InChIKey: UCDHXCFEWULFKB-UHFFFAOYSA-N
SMILES: OC(C1=NC=C(C)S1)(C2=CC=C(Cl)C=C2Cl)CN3N=CN=C3
Biological Activity:
CYP51-IN-33 is a CYP51 inhibitor with an IC50 of 0.35 μM against the sterol 14α-demethylase activity of Rhizoctonia solani CYP51. CYP51-IN-33 interferes with CYP51-associated ergosterol biosynthesis, accompanied by changes in hyphal morphology, increased membrane permeability and intracellular ROS accumulation. CYP51-IN-33 can be used in studies on CYP51-targeted antifungal activity and rice sheath blight[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CYP51-IN-33 | CYP51-IN-33 is a CYP51 inhibitor with an IC50 of 0.35 μM against the sterol 14α-demethylase activity of Rhizoctonia solani CYP51. CYP51-IN-33 interferes with CYP51-associated ergosterol biosynthesis, accompanied by changes in hyphal morphology, increased membrane permeability and intracellular ROS accumulation. CYP51-IN-33 can be used in studies on CYP51-targeted antifungal activity and rice sheath blight. |
|||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
