33421-40-8
Chemical Structure
2-Amino-5-phenylpyridine
- CAS No.: 33421-40-8
- Formula:C11H10N2
- Molecular Weight:170.21
IUPAC Name: 5-phenylpyridin-2-amine
InChIKey: OAPVIBHQRYFYSE-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC=CC=C2)C=C1
Biological Activity: 2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Amino-5-phenylpyridine | 99.91% | 2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic. | ||||||||||||||||||||
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2-Amino-5-phenylpyridine (Standard) | ≥98% | 2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic. | ||||||||||||||||||||
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2-PPA | 99.98% | 2-PPA is a lysosomal potassium and proton channel TMEM175 pore blocker. 2-PPA binds at a TMEM175 pore site to occlude potassium and proton ion permeation pathways. 2-PPA increases lysosomal macromolecule catabolism, accelerates macropinocytosis. 2-PPA binds to hepatic protein in covalent. 2-PPA can be used for the research of Parkinson's disease. | ||||||||||||||||||||
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4-Bromobiphenyl (Standard) | ≥98% | 4-Bromobiphenyl (Standard) is the analytical standard of 4-Bromobiphenyl. This product is intended for research and analytical applications. 4-Bromobiphenyl is a biological material or organic compound that can be used in life science research. | ||||||||||||||||||||
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2-Aminoquinoline | 99.95% | 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents. | ||||||||||||||||||||
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3-Aminobiphenyl | 99.91% | 3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke. | ||||||||||||||||||||
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3-Phenylphenol | 99.86% | 3-Phenylphenol is a secondary metabolite. 3-Phenylphenol can induce the hbp gene cluster in Pseudomonas sp. strain P1B16. 3-Phenylphenol can bind to the Sge1 transcription factor of Fusarium oxysporum f. sp. cubense and disrupt the function of virulence regulators. 3-Phenylphenol can be used in studies related to banana fusarium wilt. | ||||||||||||||||||||
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4-Methylbiphenyl | 99.98% | 4-Methylbiphenyl (4-Phenyltoluene) is an organic compound. 4-Methylbiphenyl has excellent chemical stability and antioxidant properties, and is widely used in industry. 4-Methylbiphenyl can serve as a solvent, coating additive, plastic additive and dye intermediate. | ||||||||||||||||||||
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[1,1'-Biphenyl]-3-amine-13C6 hydrochloride | [1,1'-Biphenyl]-3-amine-13C6 hydrochloride (Biphenyl-3-amine-13C6 hydrochloride) is the 13C labeled isotope of [1,1'-Biphenyl]-3-amine hydrochloride (HY-W106014). | |||||||||||||||||||||
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3,3'-Bipyridine | 3,3'-Bipyridine (3,3'-Dipyridyl) is a ligand used in coordination chemistry. 3,3'-Bipyridine can combine with BINOL to facilitate catalytic reactions. | |||||||||||||||||||||
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4-Phenylpyridin-2-ol | 4-Phenylpyridin-2-ol (Page 109) is a drug intermediate that can be used for the synthesis of heterocyclic compounds. | |||||||||||||||||||||
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[4,4'-bipyridin]-2-amine | [4,4'-bipyridin]-2-amine (4-Pyridin-4-yl-2-pyridinamine) is a metal-organic framework (MOF). | |||||||||||||||||||||
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References
- [1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103. [Content Brief]
- [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9. [Content Brief]