34427-61-7
Chemical Structure
Ikshusterol
Synonym(s): 7α-Hydroxysitosterol
- CAS No.: 34427-61-7
- Formula:C29H50O2
- Molecular Weight:430.71
IUPAC Name: (3S,7S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
InChIKey: SXJVFYZNUGGHRG-GDDJFQTCSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@H]3O)C
Biological Activity: Ikshusterol (7α-Hydroxysitosterol) is an oxidation product of β-sitosterol that can be generated during thermal oxidation of oils and fats. Ikshusterol exhibits weak cytotoxicity against human tumor cell lines and shows weak anti-inflammatory activity in the TPA-induced mouse ear edema in vivo model. Ikshusterol can be used in cancer-related research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ikshusterol | 95% | Ikshusterol (7α-Hydroxysitosterol) is an oxidation product of β-sitosterol that can be generated during thermal oxidation of oils and fats. Ikshusterol exhibits weak cytotoxicity against human tumor cell lines and shows weak anti-inflammatory activity in the TPA-induced mouse ear edema in vivo model. Ikshusterol can be used in cancer-related research. | ||||||||||||||||||||
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References
- [1]. Xu G, et al. Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. Journal of agricultural and food chemistry. 2009 Oct 14;57(19):9284-92. [Content Brief]
- [2]. Kimura Y, et al. Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Biological & pharmaceutical bulletin. 1995 Nov;18(11):1617-9.
- [3]. Roh EM, et al. Structural implication in cytotoxic effects of sterols from Sellaginella tamariscina. Archives of pharmacal research. 2010 Sep;33(9):1347-53.
- [4]. Oyama M, et al. β-Sitosterol Oxides From the Dried Stem of Salix gilgiana Inhibit the Proliferation of HL-60 Leukemic Cells. Current Bioactive Compounds. 2020;16(3):329-334.
