54447-85-7
Chemical Structure
Cyclic tri-AMP
- CAS No.: 54447-85-7
- Formula:C30H36N15O18P3
- Molecular Weight:987.62
IUPAC Name: (2R,3R,3aS,7aR,9R,10R,10aS,14aR,16R,17R,17aS,21aR)-2,9,16-tris(6-amino-9H-purin-9-yl)-3,5,10,12,17,19-hexahydroxydodecahydro-2H,7H,14H-trifuro[3,2-d:3',2'-j:3'',2''-p][1,3,7,9,13,15]hexaoxa[2,8,14]triphosphacyclooctadecine 5,12,19-trioxide
InChIKey: OEJXFVYXZQYNND-UQTMIEBXSA-N
SMILES: O[C@H]1[C@](O[C@@](CO[P](O)(O[C@]2([H])[C@](CO3)([H])O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@H]2O)=O)([H])[C@@]1([H])O[P](O)(OC[C@](O[C@@]6([H])N7C8=NC=NC(N)=C8N=C7)([H])[C@](O[P]3(O)=O)([H])[C@H]6O)=O)([H])N9C%10=NC=NC(N)=C%10N=C9
Biological Activity: Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity[1].
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Cyclic tri-AMP | Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity. | |||||||||||||||||||||
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