56440-60-9
56440-60-9
Chemical Structure
Aminophylline solution
- CAS No.: 56440-60-9
- Formula:C7H8N4O2·1/2C2H8N2·2H2O
- Molecular Weight:246.25
SMILES: O=C(N1C)N(C)C2=C(N=CN2)C1=O.NCCN.[1/2].O.O
Biological Activity: Aminophylline solution is mainly composed of Aminophylline dihydrate (HY-B0140A). Aminophylline is a competitive and non-selective phosphodiesterase (PDE) inhibitor. Aminophylline is a competitive adenosine receptor antagonist. Aminophylline has apulmonary vasodilator action as well as a bronchodilator action and has the potential for asthma research[1][2].
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Aminophylline solution | Aminophylline solution is mainly composed of Aminophylline dihydrate (HY-B0140A). Aminophylline is a competitive and non-selective phosphodiesterase (PDE) inhibitor. Aminophylline is a competitive adenosine receptor antagonist. Aminophylline has apulmonary vasodilator action as well as a bronchodilator action and has the potential for asthma research. | |||||||||||||||||||||
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Aminophylline dihydrate | Aminophylline Dihydrate is a competitive phosphodiesterase 3/4 (PDE3/4) inhibitor. Aminophylline Dihydrate also acts as an adenosine receptor (adenosine receptor) antagonist. Aminophylline Dihydrate elevates intracellular cAMP levels via competitive inhibition of PDE3 and PDE4, antagonizes the adenosine A1 receptor (ADORA1, regulates intracellular calcium signal transduction and synaptic vesicle recycling, upregulates the PPAR signaling pathway, and downregulates the glutamatergic synaptic pathway simultaneously. Aminophylline Dihydrate can be used in research related to major depressive disorder, epilepsy, asthma, and chronic obstructive pulmonary disease (COPD). | |||||||||||||||||||||
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