6294-17-3
6294-17-3
Chemical Structure
1-Bromo-6-chlorohexane
- CAS No.: 6294-17-3
- Formula:C6H12BrCl
- Molecular Weight:199.52
IUPAC Name: 1-bromo-6-chlorohexane
InChIKey: JTYUIAOHIYZBPB-UHFFFAOYSA-N
SMILES: ClCCCCCCBr
Biological Activity: 1-Bromo-6-chlorohexane is an α,ω-dihaloalkane and also an alkylating reagent. 1-Bromo-6-chlorohexane can be used as an intermediate in organic synthesis-related research, and can also be used as a PROTAC linker in PROTAC synthesis-related research[1][2][3][4][5].
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1-Bromo-6-chlorohexane | 99.18% | 1-Bromo-6-chlorohexane is an α,ω-dihaloalkane and also an alkylating reagent. 1-Bromo-6-chlorohexane can be used as an intermediate in organic synthesis-related research, and can also be used as a PROTAC linker in PROTAC synthesis-related research. | ||||||||||||||||||||
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References
- [1]. Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021;20(8):1367-1377. [Content Brief]
- [2]. Rose JA, et al. Direct reduction of 1-bromo-6-chlorohexane and 1-chloro-6-iodohexane at silver cathodes in dimethylformamide. Electrochimica Acta. 2016 Nov 10;218:311-7.
- [3]. Wang F, et al. Efficient preparation of unsymmetrical disulfides by nickel-catalyzed reductive coupling strategy. Nature communications. 2022 May 11;13(1):2588.
- [4]. Jia H, et al. Steric confinement-induced emission probe for monitoring protein conformations in live cells. Communications chemistry. 2026 Jan 29;9(1):109.
- [5]. Yu W, et al. Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation. Bioorganic & medicinal chemistry letters. 2021 Sep 01;47:128168.
