63372-86-1
Chemical Structure
Metamizole magnesium
Synonym(s): Dipyrone magnesium; Methamizole magnesium
- CAS No.: 63372-86-1
- Formula:C26H32MgN6O8S2
- Molecular Weight:645.00
InChIKey: NHMUJYOBLYTIKO-UHFFFAOYSA-L
SMILES: C[N](C1)(C2=C(C)N(C)N(C3=CC=CC=C3)C2=O)[Mg+2]([O-]4)([O-]S1(=O)=O)[N](CS4(=O)=O)(C5=C(C)N(C)N(C6=CC=CC=C6)C5=O)C
Biological Activity: Metamizole (Dipyrone; Methamizole) magnesium is an orally active cyclooxygenase (COX) and G6PD inhibitor. Metamizole magnesium is a potent analgesic and antipyretic agent. Metamizole magnesium inhibits cell proliferation and promotes apoptosis. Metamizole magnesium has anti-inflammatory and antioxidant activities. Metamizole sodium can be used for research on fever and various types of pain[1][2].
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Metamizole magnesium | Metamizole (Dipyrone; Methamizole) magnesium is an orally active cyclooxygenase (COX) and G6PD inhibitor. Metamizole magnesium is a potent analgesic and antipyretic agent. Metamizole magnesium inhibits cell proliferation and promotes apoptosis. Metamizole magnesium has anti-inflammatory and antioxidant activities. Metamizole sodium can be used for research on fever and various types of pain. | |||||||||||||||||||||
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References
- [1]. Ciftçi M, et al. Effects of metamizol and magnesium sulfate on enzyme activity of glucose 6-phosphate dehydrogenase from human erythrocyte in vitro and rat erythrocyte in vivo. Clinical biochemistry. 2001 Jun;34(4):297-302. [Content Brief]
- [2]. Gozzoli V, et al. Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response. Intensive care medicine. 2004 Mar;30(3):401-7. [Content Brief]
