667880-05-9
667880-05-9
Chemical Structure
SQ-030
- CAS No.: 667880-05-9
- Formula:C21H21N3O5
- Molecular Weight:395.41
InChIKey: HZFUPWRFCXZKAF-UHFFFAOYSA-N
SMILES: CC1=C(C(OC)=O)C(C2=CC=C(OCC(NC3=CC=CC=C3)=O)C=C2)NC(N1)=O
Biological Activity: SQ-030 is a cPGES inhibitor with a human Kd of 0.315 μM. SQ-030 reduces lipid accumulation in hepatocytes. SQ-030 ameliorates hepatic dysfunction, hepatic steatosis, inflammation, and fibrosis in mice. SQ-030 alleviates hepatic dysfunction and lipid deposition in mice. SQ-030 can be used for research on metabolic dysfunction-associated steatotic liver disease (MASLD)[1].
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SQ-030 | SQ-030 is a cPGES inhibitor with a human Kd of 0.315 μM. SQ-030 reduces lipid accumulation in hepatocytes. SQ-030 ameliorates hepatic dysfunction, hepatic steatosis, inflammation, and fibrosis in mice. SQ-030 alleviates hepatic dysfunction and lipid deposition in mice. SQ-030 can be used for research on metabolic dysfunction-associated steatotic liver disease (MASLD). | |||||||||||||||||||||
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