68341-09-3
68341-09-3
Chemical Structure
CuATSM
- CAS No.: 68341-09-3
- Formula:C8H14CuN6S2
- Molecular Weight:321.91
InChIKey: OGNJXAUDXXZGCW-UHFFFAOYSA-L
SMILES: CC1=[N]2[N-]C(NC)=[S][Cu+2]32[S]=C(NC)[N-][N]3=C1C
Biological Activity: CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CuATSM | 99.13% | CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities. | ||||||||||||||||||||
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IDE 2 | 99.0% | IDE 2 is a cell-permeable inducer of definitive endoderm differentiation that induces the differentiation of mouse and human embryonic stem cells into definitive endoderm. IDE2 activates the TGF‑β/Nodal signaling pathway, induces Smad2 phosphorylation, and increases Sox17 and FoxA2 expression. Endoderm induced by IDE 2 integrates into the developing gut tube, expresses gut tube markers, and differentiates into pancreatic progenitor cells. IDE 2 can be used for research related to directed endoderm differentiation of embryonic stem cells. | ||||||||||||||||||||
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BLT-1 | 99.93% | BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor. | ||||||||||||||||||||
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Gloxazone | 99.66% | Gloxazone is an effective anaplasmacide. | ||||||||||||||||||||
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Ambazone monohydrate | Ambazone monohydrate is an orally active membrane active antitumor agent. Ambazone monohydrate also shows antibacterial and weak antiviral activities. | |||||||||||||||||||||
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Ambazone | 97.60% | Ambazone is an orally active membrane active antitumor agent. Ambazone also shows antibacterial and weak antiviral activities. | ||||||||||||||||||||
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CuATSP | 99.43% | CuATSP, a potent inhibitor of ferroptotic cell death, is almost 20-fold more potent than CuATSM. | ||||||||||||||||||||
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ATSM | 98.76% | ATSM is a ligand that forms complexes with Cu2+, Ni2+, Zn2+, and Fe2+, with the highest affinity for Cu2+. ATSM forms Cu-ATSM with copper, which is used for PET imaging to detect tumor hypoxia. ATSM is commonly used in coordination chemistry and radiopharmaceutical research. | ||||||||||||||||||||
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(E,E)-ATSM | (E,E)-ATSM is a chelating agent. (E,E)-ATSM can react with the metallized ligand Copper gluconate. (E,E)-ATSM can be used in research on central nervous system diseases. | |||||||||||||||||||||
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Hexacyclen | 98.0% | Hexacyclen is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications. | ||||||||||||||||||||
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Hexacyclen hexahydrochloride | Hexacyclen (Cycloalkene) is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. Hexacyclen is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions, and is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Hexacyclen also acts as an inhibitor of cancer. | |||||||||||||||||||||
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References
- [1]. Zilka O, et al. Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death. J Am Chem Soc. 2021 Nov 17;143(45):19043-19057. [Content Brief]
- [2]. Shi X, et al., Neuroprotective effect of CuATSM in mice stroke model by ameliorating oxidative stress. Neurosci Res. 2021 May;166:55-61. [Content Brief]
