8067-12-7
Chemical Structure
Ascorutin
Synonym(s): Rutascorbin
- CAS No.: 8067-12-7
- Formula:C33H38O22
- Molecular Weight:786.64
IUPAC Name: (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one compound with 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one (1:1)
InChIKey: USMZEYPOTJAYPT-LRROQMAJSA-N
SMILES: OC[C@@H]([C@]1([H])C(O)=C(C(O1)=O)O)O.O=C(C(O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O)=C(C4=CC(O)=C(C=C4)O)OC5=CC(O)=C6)C5=C6O
Biological Activity: Ascorutin (Rutascorbin) is an orally effective antioxidant and anti-inflammatory agent composed of a combination of ascorbic acid and rutin. Ascorutin, based on the synergistic action of ascorbic acid and rutin, comprehensively enhances and regulates local and systemic immune function by reducing oxidative stress, modulating calcium-phosphorus metabolism, and inhibiting the release of inflammatory mediators. Ascorutin can be used in the study of periodontitis[1][2][3][4].
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Ascorutin | Ascorutin (Rutascorbin) is an orally effective antioxidant and anti-inflammatory agent composed of a combination of ascorbic acid and rutin. Ascorutin, based on the synergistic action of ascorbic acid and rutin, comprehensively enhances and regulates local and systemic immune function by reducing oxidative stress, modulating calcium-phosphorus metabolism, and inhibiting the release of inflammatory mediators. Ascorutin can be used in the study of periodontitis. | |||||||||||||||||||||
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References
- [1]. Shanaida YV, et al. Changes in the concentrations of calcium and phosphorus during modeling of periodontal tissue disease and its correction. Ukrainian Dental Almanac. 2025 Dec 31(4):24-37.
- [2]. Шанайда ЮВ, et al. Study of ceruloplasmin activity in experimental periodontitis and after its correction. Харківський стоматологічний журнал. 2025 Dec 30;2(4 (6)):606-17.
- [3]. Maslov O, et al. Investigation the influence of biologically active compounds on the antioxidant, antibacterial and anti-inflammatory activities of red raspberry (Rubus idaeus L.) leaf extract. Curr Issues Pharm Med Sci. 2022;35(4):229-35.
- [4]. Malko NV, et al. Estimation of influence of the therapeutic–prophylactic complex on the immune system indices of experimental animals with simulated gingivitis. Ukrainian Dental Almanac. 2018 Jun 25(2):9-12.
