824961-52-6
824961-52-6
Chemical Structure
BCD38
- CAS No.: 824961-52-6
- Formula:C23H19N5O
- Molecular Weight:381.43
InChIKey: NAPUJOHOSNNFEY-VCHYOVAHSA-N
SMILES: CC1=CC(/C=C(C2=NC3=CC=CC=C3N2)\C#N)=C(N1C4=C(C(C)=C(O4)C)C#N)C
Biological Activity: BCD38 is a selective DHX33 inhibitor with an IC50 of 0.8 μM and a Kd value of 4.7 μM. BCD38 is applicable to lung cancer-related research[1][2].
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BCD38 | BCD38 is a selective DHX33 inhibitor with an IC50 of 0.8 μM and a Kd value of 4.7 μM. BCD38 is applicable to lung cancer-related research. | |||||||||||||||||||||
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References
- [1]. Wang X, et al. DHX33 inhibitors induced transcriptional changes for a subset of genes in cancer cells. Scientific reports. 2026 Jun 05. [Content Brief]
- [2]. Wang Y, et al. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents. Bioorganic & medicinal chemistry letters. 2023 Nov 15;96:129505. [Content Brief]
