832680-32-7
832680-32-7
Chemical Structure
SBI-5844
Synonym(s): SBI-1275844
- CAS No.: 832680-32-7
- Formula:C22H25NO2
- Molecular Weight:335.44
InChIKey: DAFBTFAOHKOWSJ-UHFFFAOYSA-N
SMILES: O=C(C)C1=CN(CCCOC2=C(C)C=CC=C2)C3=C1C=CC=C3CC
Biological Activity: SBI-5844 (SBI-1275844) is a eIF4F complex inhibitor and antiviral agent. SBI-5844 disrupts the assembly of the eIF4F complex and blocks the interaction between eIF4E and eIF4G. SBI-5844 inhibits the synthesis of HCoV-OC43 nucleocapsid protein and reduces the levels of HCoV-OC43 RNA and total protein. SBI-5844 can be used in studies related to human coronavirus OC43 (HCoV-OC43) infection[1].
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SBI-5844 | SBI-5844 (SBI-1275844) is a eIF4F complex inhibitor and antiviral agent. SBI-5844 disrupts the assembly of the eIF4F complex and blocks the interaction between eIF4E and eIF4G. SBI-5844 inhibits the synthesis of HCoV-OC43 nucleocapsid protein and reduces the levels of HCoV-OC43 RNA and total protein. SBI-5844 can be used in studies related to human coronavirus OC43 (HCoV-OC43) infection. | |||||||||||||||||||||
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