847440-99-7
847440-99-7
Chemical Structure
A-837093 sodium
- CAS No.: 847440-99-7
- Formula:C24H26N3NaO6S2
- Molecular Weight:539.60
InChIKey: QAKKZLYQACLLSU-GJFSDDNBSA-M
SMILES: O=C1C(C(NC2=CC=C(NS(C)(=O)=O)C=C23)=NS3(=O)=O)=C(C4=CC=CC=C4[C@@]1(C)CCC(C)C)O[Na]
Biological Activity: A-837093 sodium is a potent and orally active inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase. A-837093 sodium shows potencies against polymerases derived from both HCV genotypes 1a (IC50 = 1.25 nM) and 1b (IC50 = 0.33 nM). A-837093 sodium exhibits antiviral efficacy in HCV-infected chimpanzees. A-837093 sodium can be used for HCV infection research[1].
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A-837093 sodium | A-837093 sodium is a potent and orally active inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase. A-837093 sodium shows potencies against polymerases derived from both HCV genotypes 1a (IC50 = 1.25 nM) and 1b (IC50 = 0.33 nM). A-837093 sodium exhibits antiviral efficacy in HCV-infected chimpanzees. A-837093 sodium can be used for HCV infection research. | |||||||||||||||||||||
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