852231-29-9
852231-29-9
Chemical Structure
c-Met/STAT3-IN-1
- CAS No.: 852231-29-9
- Formula:C22H19FN4S
- Molecular Weight:390.48
InChIKey: TURJYWUUMGVFRH-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=CSC3=NC=NC(N4CCN(C5=CC=CC=C5)CC4)=C32)C=C1
Biological Activity: c-Met/STAT3-IN-1 is a c-Met/STAT3 inhibitor with IC50 values of 0.79 μM and 0.67 μM, respectively. c-Met/STAT3-IN-1 inhibits the phosphorylation of c-Met receptor tyrosine kinase and STAT3 transcription factor, induces apoptosis, necrotic cell death, and G2/M cell cycle arrest. c-Met/STAT3-IN-1 can be used for research on colorectal cancer[1].
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c-Met/STAT3-IN-1 | c-Met/STAT3-IN-1 is a c-Met/STAT3 inhibitor with IC50 values of 0.79 μM and 0.67 μM, respectively. c-Met/STAT3-IN-1 inhibits the phosphorylation of c-Met receptor tyrosine kinase and STAT3 transcription factor, induces apoptosis, necrotic cell death, and G2/M cell cycle arrest. c-Met/STAT3-IN-1 can be used for research on colorectal cancer. | |||||||||||||||||||||
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