87085-00-5
Chemical Structure
Mulberrofuran G
- CAS No.: 87085-00-5
- Formula:C34H26O8
- Molecular Weight:562.57
IUPAC Name: (3aR,3a1S,8aS,13bR)-8a-(2,4-dihydroxyphenyl)-6-(6-hydroxybenzofuran-2-yl)-2-methyl-1,3a1,8a,13b-tetrahydro-3aH-benzo[3,4]isochromeno[1,8-bc]chromene-4,11-diol
InChIKey: MJJWBJFYYRAYKU-OPKNDJPNSA-N
SMILES: OC1=C(C=CC(O)=C1)[C@]23[C@]4([H])[C@](C=C(C)C[C@@]4([H])C5=C(C=C(O)C=C5)O3)([H])C6=C(O)C=C(C7=CC8=C(C=C(O)C=C8)O7)C=C6O2
Biological Activity: Mulberrofuran G is a NOX inhibitor (IC50: 6.9 μM) and tyrosinase inhibitor. Mulberrofuran G exhibits anti-inflammatory, antioxidant, antiviral, antitumor, and neuroprotective effects. Mulberrofuran G can be used in the research of tumors, nervous system diseases, and other conditions[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mulberrofuran G | 97.86% | Mulberrofuran G is a NOX inhibitor (IC50: 6.9 μM) and tyrosinase inhibitor. Mulberrofuran G exhibits anti-inflammatory, antioxidant, antiviral, antitumor, and neuroprotective effects. Mulberrofuran G can be used in the research of tumors, nervous system diseases, and other conditions. | ||||||||||||||||||||
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References
- [1]. Geng CA, et al. Mulberrofuran G and isomulberrofuran G from Morus alba L.: anti-hepatitis B virus activity and mass spectrometric fragmentation. J Agric Food Chem. 2012;60(33):8197-8202. [Content Brief]
- [2]. HaiYuanBo G, et al. Mulberrofuran G inhibits proliferation and migration by inactivating JAK2/STAT3 signaling in lung cancer cells. Bangladesh Journal of Pharmacology, 2021, 16(4): 134-140.
- [3]. Kim YS, et al. Mulberrofuran G, a Mulberry Component, Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor. Nutrients. 2022 Oct 7;14(19):4170. [Content Brief]
- [4]. Hong S, et al. Mulberrofuran G Protects Ischemic Injury-induced Cell Death via Inhibition of NOX4-mediated ROS Generation and ER Stress. Phytother Res. 2017;31(2):321-329. [Content Brief]
- [5]. Koirala P, et al. Structure⁻Activity Relationship of the Tyrosinase Inhibitors Kuwanon G, Mulberrofuran G, and Albanol B from Morus Species: A Kinetics and Molecular Docking Study. Molecules. 2018 Jun 11;23(6):1413. [Content Brief]
