874968-47-5
Chemical Structure
Antibacterial agent 361
- CAS No.: 874968-47-5
- Formula:C15H16ClNO2
- Molecular Weight:277.75
IUPAC Name: ethyl 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylate
InChIKey: CEHATKSXJJTJFH-UHFFFAOYSA-N
SMILES: O=C(OCC)C1CC=2C=3C=C(Cl)C=CC3NC2CC1
Biological Activity: Antibacterial agent 361 is an antibacterial agent as well as a membrane-permeable prodrug. Antibacterial agent 361 binds to subsite I of the linear motif binding pocket of the Escherichia coli sliding clamp, disrupts the interaction between the sliding clamp and its chaperone protein, and inhibits sliding clamp-dependent in vitro DNA replication. Antibacterial agent 361 can be used in the research of bacterial infections[1].
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Antibacterial agent 361 | Antibacterial agent 361 is an antibacterial agent as well as a membrane-permeable prodrug. Antibacterial agent 361 binds to subsite I of the linear motif binding pocket of the Escherichia coli sliding clamp, disrupts the interaction between the sliding clamp and its chaperone protein, and inhibits sliding clamp-dependent in vitro DNA replication. Antibacterial agent 361 can be used in the research of bacterial infections. | |||||||||||||||||||||
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