881835-86-5
881835-86-5
Chemical Structure
4,6-Dioxoheptanoic acid-13C5
Synonym(s): Succinylacetone-13C5
- CAS No.: 881835-86-5
- Formula:C213C5H10O4
- Molecular Weight:163.12
IUPAC Name: 4,6-dioxoheptanoic-3,4,5,6,7-13C5 acid
InChIKey: WYEPBHZLDUPIOD-JBSMRZEESA-N
SMILES: O=[13C]([13CH2][13C]([13CH3])=O)[13CH2]CC(O)=O
Biological Activity: 4,6-Dioxoheptanoic acid-13C5 is the 13C labeled 4,6-Dioxoheptanoic acid[1]. 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4,6-Dioxoheptanoic acid-13C5 | 99.8% | 4,6-Dioxoheptanoic acid-13C5 is the 13C labeled 4,6-Dioxoheptanoic acid. 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. | ||||||||||||||||||||
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4,6-Dioxoheptanoic acid (Standard) | 99.02% | 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. | ||||||||||||||||||||
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4,6-Dioxoheptanoic acid | 98.81% | 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. | ||||||||||||||||||||
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Oxoadipic acid | 99.86% | Oxoadipic acid is a key intermediate metabolite in the lysine degradation pathway. The level of Oxoadipic acid is significantly negatively correlated with the abundance of Staphylococcus. That is, the higher the abundance of Staphylococcus-a potential pathogenic bacterium that usually increases in ulcerative colitis-the lower the level of Oxoadipic acid. Oxoadipic acid can be used in the research of ulcerative colitis. | ||||||||||||||||||||
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Oxoadipic acid (Standard) | 99.66% | Oxoadipic acid (Standard) is the analytical standard of Oxoadipic acid. This product is intended for research and analytical applications. Oxoadipic acid is a key intermediate metabolite in the lysine degradation pathway. The level of Oxoadipic acid is significantly negatively correlated with the abundance of Staphylococcus. That is, the higher the abundance of Staphylococcus-a potential pathogenic bacterium that usually increases in ulcerative colitis-the lower the level of Oxoadipic acid. Oxoadipic acid can be used in the research of ulcerative colitis. | ||||||||||||||||||||
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Glurate | 98.54% | Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid. | ||||||||||||||||||||
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Glurate (Standard) | ≥98% | Glurate (Standard) is the analytical standard of Glurate (HY-W001957). This product is used for research and analytical applications. Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid. | ||||||||||||||||||||
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3-Oxopentanedioic acid | 97.0% | 3-Oxopentanedioic acid is a dicarboxylic acid that is easily brominated. 3-Oxopentanedioic acid can be used as an intermediate in organic chemical synthesis. | ||||||||||||||||||||
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2-Ketoglutaric acid-13C5 | 99.92% | 2-Ketoglutaric acid-13C5 (Alpha-Ketoglutaric acid-13C5) is a 13C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). | ||||||||||||||||||||
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2-Ketoglutaric acid-13C | 2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). | |||||||||||||||||||||
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2-Ketoglutaric acid-13C2 | 2-Ketoglutaric acid-13C2 (Alpha-Ketoglutaric acid-13C2) is a 13C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). | |||||||||||||||||||||
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3-Ketoadipic acid | 98.69% | 3-Ketoadipic acid is a dicarboxylic acid containing a keto group that can be isolated from Brazilian propolis (Et-Bra). Brazilian propolis exhibits antibacterial, antifungal, and antiparasitic activities. | ||||||||||||||||||||
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Levulinic acid-13C3 | Levulinic acid-13C3 (4-Oxovaleric acid-13C) is the 13C-labeled Levulinic acid (HY-Y0839). Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate. Levulinic acid is also a 5-keto-pentanoic acid. Levulinic acid can be utilized by the cells as a cosubstrate for biopolymer synthesis. Levulinic acid can be used in antibacterial research. | |||||||||||||||||||||
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Levulinic acid | 99.95% | Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate. Levulinic acid is also a 5-keto-pentanoic acid. Levulinic acid can be utilized by the cells as a cosubstrate for biopolymer synthesis. Levulinic acid can be used in antibacterial research. | ||||||||||||||||||||
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Levulinic acid (Standard) | 99.27% | Levulinic acid (Standard) is the analytical standard of Levulinic acid. This product is intended for research and analytical applications. Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90. [Content Brief]
