Coumarin-based kinetic stabilizer-1
Coumarin-based kinetic stabilizer-1 is an immunoglobulin light chain dimer stabilizer (human EC50 = 1880 nM) that stabilizes native LC dimers by binding to the VL-VL interface, reduces misfolding and proteolysis, and prevents aggregation of amyloidogenic light chains. Coumarin-based kinetic stabilizer-1 can be used in research on immunoglobulin light chain amyloidosis.
For research use only. We do not sell to patients.
- CAS No.: 2495749-21-6
- Formula: C26H30N6O5
- Molecular Weight:506.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2495749-21-6
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Molecular Weight 506.55
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Formula C26H30N6O5
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SMILES
O=C1OC2=C(C(C)=C1CCN3C(NC4(CN(CC4)C(C5=CN=CN5)=O)C3=O)=O)C=CC(N(CC)CC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Coumarin-based kinetic stabilizer-1 Related Classifications
HY-186370 Related Classifications
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Keywords
- Coumarin-based kinetic stabilizer-1
- 2495749-21-6
- Biochemical Assay Reagents
- VL-VL interface
- WIL-FL
- aggregation
- amyloidogenic immunoglobulin light chains
- fold protection assay
- immunoglobulin light-chain amyloidosis
- immunoglobulin light-chain dimer stabilizer
- misfolding
- proteinase K proteolysis
- proteolysis
- Inhibitor
- inhibitor
- inhibit