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Cat. No.: HY-133077

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Diethylcarbamazine N-oxide

Name: Diethylcarbamazine N-oxide
Brand: MedChemExpress
SKU: HY-133077
Availability: PreOrder

(Synonyms: DEC N-oxide)

Diethylcarbamazine N-oxide (DEC N-oxide) is the N-oxide metabolite of Diethylcarbamazine (HY-12642A). Diethylcarbamazine N-oxide is stable to extraction in alkalinized urine but with low efficiency, and can be converted to Diethylcarbamazine upon thermal decomposition or reduction by sulfur dioxide. Diethylcarbamazine N-oxide can be used for the study of Diethylcarbamazine metabolism.

For research use only. We do not sell to patients.

CAS No.: 34812-73-2
Formula: C₁₀H₂₁N₃O₂
Molecular Weight:215.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Diethylcarbamazine N-oxide Chemical Structure

CAS No.: 34812-73-2

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Biological Activity
- Description
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Chemical Information
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Biological Activity

Description

In Vitro

Diethylcarbamazine N-oxide (DEC N-oxide) can be reduced to Diethylcarbamazine by SO₂ in urine or aqueous solution^[2].
Diethylcarbamazine N-oxide has a TLC R_F of 0.25, and g.l.c. retention times of 23.7 min (major) and 31.8 min (minor)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 34812-73-2
Molecular Weight 215.29
Formula C₁₀H₂₁N₃O₂
SMILES

O=C(N1CC[N+](CC1)([O-])C)N(CC)CC
Synonyms

DEC N-oxide
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Edwards G, et al. Identification and quantification of diethylcarbamazine and diethylcarbamazine N-oxide in rat urine. Xenobiotica. 1981 Apr;11(4):281-4.

[2]. Faulkner JK, et al. Dealkylation and N-oxidation in the metabolism of i-diethylcarbamyl-4-methylpiperazine in the rat. Xenobiotica. 1972 Jan;2(1):59-68.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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