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Cat. No.: HY-W019852R

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Flutriafol (Standard)

Name: Flutriafol (Standard)
Brand: MedChemExpress
SKU: HY-W019852R
Price: 40.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Flutriafol (Standard) is the analytical standard of Flutriafol (HY-W019852). This product is intended for research and analytical applications. Flutriafol is an orally active triazole fungicide. Flutriafol blocks the biosynthesis of ergosterol, cholesterol, and steroids by inhibiting CYP51, thereby inhibiting fungal cell membrane formation and exhibiting antifungal activity. Flutriafol induces oxidative stress, mitochondrial depolarization, and apoptosis in hepatocellular carcinoma cells. Flutriafol also modulates dopamine release and reduces plasma cholesterol, triglycerides, and carotenoid eye ring pigmentation. Flutriafol can be used in research related to fungal infections and non-alcoholic fatty liver disease.

For research use only. We do not sell to patients.

Purity : 95%
CAS No.: 76674-21-0
Formula: C₁₆H₁₃F₂N₃O
Molecular Weight:301.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Flutriafol (Standard) Chemical Structure

CAS No.: 76674-21-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-W019852
Flutriafol

CYP51 Inhibitor

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 76674-21-0
Molecular Weight 301.29
Formula C₁₆H₁₃F₂N₃O
SMILES

OC(C1=CC=C(F)C=C1)(C2=CC=CC=C2F)CN3N=CN=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Kwon HC, et al. Effects of Flutriafol Fungicide on the Lipid Accumulation in Human Liver Cells and Rat Liver. Foods (Basel, Switzerland). 2021 Jun 10;10(6):1346.

[2]. Lopez-Antia A, et al. Brood size is reduced by half in birds feeding on flutriafol-treated seeds below the recommended application rate. Environmental pollution (Barking, Essex : 1987). 2018 Dec;243(Pt A):418-426.

[3]. Faro LR, et al. Role of ionotropic glutamatergic receptors and nitric oxide in the effects of flutriafol, a triazole fungicide, on the in vivo striatal dopamine release. The Journal of toxicological sciences. 2012;37(6):1135-42. [Content Brief]

[4]. Ktari N, et al. Integrated UPLC-Q-TOF MS/MS and computational analysis identify antioxidant peptides from Salaria basilisca protein hydrolysate with protection against flutriafol-induced oxidative stress. Results in Chemistry. 2026 Aug 26:103790.

[5]. Guo H, et al. Synthesis and bacteriostatic activities of modified flutriafol derivatives. ACS Omega. 2019 Jan 31;4(1):9-14.

[6]. Ktari N, et al. Subacute oral toxicity of flutriafol in mice: Behavioral, biochemical, and histological alterations. Toxicology and industrial health. 2026 Mar;42(3):61-81.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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