TMEM266 - transmembrane protein 266 Gene

Also Known as HVRP1; HsHVRP1; C15orf27; hTMEM266

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 123591

Summary

Enables protein homodimerization activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in cytosol; dendrite; and plasma membrane. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in placenta (RPKM 1.7), testis (RPKM 1.2) and 14 other tissues.

TMEM266 Products (1)

mRNA Protein Name
NM_152335.5 NP_689548.3 transmembrane protein 266

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables channel activity IDA
IDA: Inferred from direct assay
25165868 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
30810529 GOA
NOT enables voltage-gated channel activity IDA
IDA: Inferred from direct assay
30810529 GOA
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
25165868 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
25165868 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM266 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM266 Q2M3C6 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
TMEM266 Q2M3C6 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
TMEM266 Q2M3C6 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
TMEM266 Q2M3C6 KDM1A Homo sapiens O60341
Y2H Prey Pooling
32296183
Intra
TMEM266 Q2M3C6 KDM1A Homo sapiens O60341
Y2H Array
32296183
Intra
TMEM266 Q2M3C6 KDM1A Homo sapiens O60341
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14699 TMEM216 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14705 TMEM236 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14713 TMEM26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14714 TMEM260 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14715 TMEM263 Human Pre-designed siRNA Set A Pre-designed Set / Unkown