Zkscan17 - zinc finger with KRAB and SCAN domains 17 Gene

Also Known as Nizp1; Zfp496; Znf496

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268417

Summary

Enables DNA binding activity and identical protein binding activity. Involved in positive regulation of DNA-templated transcription. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nuclear body. Is expressed in several structures, including 2-cell stage conceptus; 4-8 cell stage conceptus; blastocyst-stage conceptus; genitourinary system; and morula-stage conceptus. Orthologous to human ZNF496 (Zinc Finger Protein 496). [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis adult (RPKM 32.5), ovary adult (RPKM 10.5) and 28 other tissues.

Zkscan17 Products (3)

mRNA Protein Name
NM_001130529.2 NP_001124001.1 zinc finger protein 496 isoform 2
NM_001291014.1 NP_001277943.1 zinc finger protein 496 isoform 3
NM_172941.4 NP_766529.3 zinc finger protein 496 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
17521633 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17521633 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
17521633 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17521633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Zkscan17 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Znf496 Q5SXI5 Jarid2 Mus musculus Q62315
Pull Down
17521633
Intra
Znf496 Q5SXI5 Jarid2 Mus musculus Q62315
Anti Tag CoIP
17521633
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16081 ZKSCAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown