ANKRD13D - ankyrin repeat domain 13D Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338692

Summary

The protein encoded by this gene is a member of the ankyrin repeat domain (ANKRD) 13 family, which currently consists of four proteins containing ubiquitin-interacting motifs. These proteins are integral membrane proteins that bind specifically to Lys-63-linked ubiquitin chains on membrane-bound proteins, targeting those proteins for rapid internalization. [provided by RefSeq, Dec 2016]
Broad expression in bone marrow (RPKM 36.3), spleen (RPKM 13.6) and 23 other tissues.

ANKRD13D Products (1)

mRNA Protein Name
NG_052619.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
enables ubiquitin-modified protein reader activity IDA
IDA: Inferred from direct assay
22298428 GOA
enables ubiquitin-modified protein reader activity IPI
IPI: Inferred from physical interaction
22298428 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of receptor internalization IMP
IMP: Inferred from mutant phenotype
22298428 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22298428 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22298428 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
22298428 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANKRD13D Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ANKRD13D Q6ZTN6 ENTREP1 Homo sapiens Q15884
Y2H
34927784
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00715 ANKRD13A Human Pre-designed siRNA Set A Pre-designed Set / Unkown