PKM - pyruvate kinase M1/2 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 403874

About PKM

Primary_assembly 30: 35,912,436-35,944,108 reverse strand.ROS_Cfam_1.0:CM025129.1

This gene has 5 transcripts (splice variants), 301 orthologues and 2 paralogues.

PKM Products (2)

mRNA Protein Name
XM_038442865.1 XP_038298793.1 pyruvate kinase PKM isoform X1
XM_038442866.1 XP_038298794.1 pyruvate kinase PKM isoform X2

PKM Protein Structure

Pyruvate_Kinase

Pyruvate_Kinase: cd00288 (101 - 589)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 591 a.a.
Protein Preferred Names Protein Names

pyruvate kinase PKM

  • pyruvate kinase M

  • pyruvate kinase, muscle

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0404A Benserazide hydrochloride Inhibitor 99.68% Yes
HY-B0404AR Benserazide hydrochloride (Standard) Inhibitor 99.89% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-121275 Benserazide Inhibitor 98.43% Phase 4
HY-155785 MTP / Phase 4
HY-P1284A ZIP TFA Inhibitor / Phase 4

Pre-clinical Phase

Bioactive Molecules (63)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0822 Shikonin Inhibitor 99.80% Unkown
HY-18657 TEPP-46 Activator 99.77% Unkown
HY-103617 PKM2-IN-1 Inhibitor 99.79% Unkown
HY-19330 DASA-58 Activator 99.57% Unkown
HY-126585 SAICAR 99.57% Unkown
HY-162080 METTL1-WDR4-IN-1 Inhibitor 99.61% Unkown
HY-N7108 7-Hydroxyflavone 99.89% Unkown
HY-P1284 ZIP Inhibitor 98.56% Unkown
HY-157913 PKM2-IN-6 99.95% Unkown
HY-147368 PKM2 activator 2 Activator 99.38% Unkown
HY-167832 PT109 99.20% Unkown
HY-N4185 Licoflavone A 99.95% Unkown
HY-139667 PKM2-IN-3 Inhibitor 99.44% Unkown
HY-N2552 Vitamin K5 hydrochloride 99.25% Unkown
HY-D1456 TEPC466 99.81% Unkown
HY-N3011 Iridin 99.72% Unkown
HY-N7064 Iminostilbene Inhibitor 99.66% Unkown
HY-148324 PKM2 activator 5 Activator 96.03% Unkown
HY-148615 NPD10084 Inhibitor 99.69% Unkown
HY-155850 CIAC001 Inhibitor 99.70% Unkown
HY-W587878 Thujopsene 86.31% Unkown
HY-P1399A Pep2m, myristoylated TFA Inhibitor 99.77% Unkown
HY-126585S SAICAR-d3 96.57% Unkown
HY-132215 PF-06284674 Activator 99.69% Unkown
HY-156375 PKM2 activator 6 / Unkown
HY-162080A METTL1-WDR4-IN-1 TFA Inhibitor 99.61% Unkown
HY-179371 LIQ1 Inhibitor 97.40% Unkown
HY-D1876 ZY-2 95.77% Unkown
HY-RS10602 PKM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119874 Alkannin Inhibitor / Unkown
HY-147397 PKM2 activator 3 Activator / Unkown
HY-149275 PKM2/PDK1-IN-1 / Unkown
HY-155216 PKM2 activator 10 Activator / Unkown
HY-155849 PKM2-IN-4 Inhibitor / Unkown
HY-161519 PKM2 activator 7 Activator / Unkown
HY-168882 PKM2 modulator 1 / Unkown
HY-168883 PKM2 modulator 2 / Unkown
HY-169567 PKM2-IN-9 Inhibitor / Unkown
HY-170577 PKM2-IN-8 / Unkown
HY-172881 PKM2-IN-10 Inhibitor / Unkown
HY-178441 PKM2-IN-11 / Unkown
HY-178748 PKM2-IN-12 / Unkown
HY-180523 PKM2-IN-13 / Unkown
HY-180795 PKM2 activator 11 / Unkown
HY-182037 Multi-target kinase-IN-9 Inhibitor / Unkown
HY-183765 PARP1/PKM2-IN-1 Inhibitor / Unkown
HY-186335 PKM2 activator 12 / Unkown
HY-B0404AS Benserazide-d3 hydrochloride Inhibitor / Unkown
HY-B1814 Vitamin K5 / Unkown
HY-D1877 ZY-1 98.91% Unkown
HY-DY1120 ZY-2 (solution) Activator / Unkown
HY-P12310 Ac-PKM-AMC Substrate / Unkown
HY-P1399 Pep2m, myristoylated Inhibitor / Unkown
HY-RS10603 Pkm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10604 Pkm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W753956 Iminostilbene-d10 / Unkown
HY-129165 ZINC08383544 / Unkown
HY-148313 PKM2 activator 4 Activator 99.94% Unkown
HY-162071 PKM2-IN-5 Inhibitor / Unkown
HY-168995 BAR-072 Inhibitor / Unkown
HY-169883 PKM2-IN-7 Inhibitor / Unkown
HY-180796 PKM2 agonist-1 Agonist / Unkown
HY-18657R TEPP-46 (Standard) Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PKM NCBI NCBI:5315