TMED5 - transmembrane p24 trafficking protein 5 Gene

Also Known as p28; p24g2; CGI-100

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50999

Summary

Involved in Golgi ribbon formation. Located in cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in kidney (RPKM 22.0), thyroid (RPKM 21.2) and 25 other tissues.

TMED5 Products (3)

mRNA Protein Name
NM_001167830.2 NP_001161302.1 transmembrane emp24 domain-containing protein 5 isoform 2 precursor
NM_001410825.1 NP_001397754.1 transmembrane emp24 domain-containing protein 5 isoform 3 precursor
NM_016040.5 NP_057124.3 transmembrane emp24 domain-containing protein 5 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23455924 GOA
Biological Process GO Annotation Evidence References Source
involved in Golgi ribbon formation IMP
IMP: Inferred from mutant phenotype
19948005 GOA
Cellular Component GO Annotation Evidence References Source
located in cis-Golgi network IDA
IDA: Inferred from direct assay
19948005 GOA
located in endoplasmic reticulum exit site IDA
IDA: Inferred from direct assay
19948005 GOA
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
15308636 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMED5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMED5 Q9Y3A6 PRMT6 Homo sapiens Q96LA8
Y2H
23455924
Intra
TMED5 Q9Y3A6 PRMT6 Homo sapiens Q96LA8
Anti Tag CoIP
23455924
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14635 TMED10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14634 TMED1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14636 TMED2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14637 TMED3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14638 TMED4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14639 TMED7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14640 TMED9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19242 Tmed1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19272 Tmed10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20501 Tmed4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21788 Tmed2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21789 Tmed3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21790 Tmed9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25731 Tmed1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25761 Tmed10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27009 Tmed4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28304 Tmed2 Rat Pre-designed siRNA Set A / Unkown
HY-RS28305 Tmed3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28306 Tmed9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown