ATP8B2 - ATPase phospholipid transporting 8B2 Gene

Also Known as ATPID

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57198

Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Ubiquitous expression in ovary (RPKM 16.7), endometrium (RPKM 13.3) and 23 other tissues.

ATP8B2 Products (5)

mRNA Protein Name
NM_001005855.2 NP_001005855.1 phospholipid-transporting ATPase ID isoform b
NM_001367934.1 NP_001354863.1 phospholipid-transporting ATPase ID isoform c
NM_001370596.1 NP_001357525.1 phospholipid-transporting ATPase ID isoform d
NM_001370597.1 NP_001357526.1 phospholipid-transporting ATPase ID isoform e
NM_001372009.1 NP_001358938.1 phospholipid-transporting ATPase ID isoform e

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatidylcholine flippase activity IDA
IDA: Inferred from direct assay
25315773 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20947505 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
20947505 GOA
part of phospholipid-translocating ATPase complex IPI
IPI: Inferred from physical interaction
20961850 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
20947505 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATP8B2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ATP8B2 P98198 TMEM30A Homo sapiens Q9NV96
Confocal
20961850
Intra
ATP8B2 P98198 TMEM30A Homo sapiens Q9NV96
Anti Tag CoIP
20961850
Intra
ATP8B2 P98198 TMEM30A Homo sapiens Q9NV96
Confocal
20947505
Intra
ATP8B2 P98198 TMEM30B Homo sapiens Q3MIR4
Anti Tag CoIP
20947505
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01187 ATP1B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01195 ATP2B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01238 ATP8A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01239 ATP8B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01240 ATP8B4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21823 Atp1b2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28340 Atp1b2 Rat Pre-designed siRNA Set A / Unkown