NIBAN2 - niban apoptosis regulator 2 Gene
Also Known as OC58; MEG-3; C9orf88; FAM129B; MINERVA; bA356B19.6
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 64855
Summary
Enables transcription coactivator activity. Involved in several processes, including gonadotropin secretion; negative regulation of DNA biosynthetic process; and regulation of DNA-templated transcription. Located in several cellular components, including adherens junction; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in esophagus (RPKM 167.0), lung (RPKM 55.7) and 20 other tissues.
NIBAN2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001035534.3 | NP_001030611.1 | protein Niban 2 isoform 2 |
| NM_022833.4 | NP_073744.2 | protein Niban 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
19615732 | GOA |
| enables transcription coactivator activity |
IDA
IDA: Inferred from direct assay
|
17569660 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in gonadotropin secretion |
IEP
IEP: Inferred from expression pattern
|
14602737 | GOA |
| involved in gonadotropin secretion |
IMP
IMP: Inferred from mutant phenotype
|
18628527 | GOA |
| involved in negative regulation of DNA biosynthetic process |
IDA
IDA: Inferred from direct assay
|
14602737 | GOA |
| involved in negative regulation of DNA-templated transcription |
IDA
IDA: Inferred from direct assay
|
17569660 | GOA |
| involved in negative regulation of apoptotic process |
IMP
IMP: Inferred from mutant phenotype
|
21148485 | GOA |
| involved in negative regulation of cell population proliferation |
IDA
IDA: Inferred from direct assay
|
14602737 | GOA |
| involved in positive regulation of DNA-templated transcription |
IDA
IDA: Inferred from direct assay
|
17569660 | GOA |
| involved in positive regulation of transcription regulatory region DNA binding |
IDA
IDA: Inferred from direct assay
|
17569660 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in adherens junction |
IDA
IDA: Inferred from direct assay
|
21148485 | GOA |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
14602737 | GOA |
| located in cytosol |
IDA
IDA: Inferred from direct assay
|
21148485 | GOA |
| NOT located in nucleus |
IDA
IDA: Inferred from direct assay
|
21148485 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
14602737 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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NIBAN2 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
NIBAN2 | Q96TA1 | KEAP1 | Homo sapiens | Q14145 | 31262713 | |
|
Intra
|
NIBAN2 | Q96TA1 | KEAP1 | Homo sapiens | Q14145 | 31262713 | |
|
Intra
|
NIBAN2 | Q96TA1 | KEAP1 | Homo sapiens | Q14145 | 31262713 | |
|
Intra
|
NIBAN2 | Q96TA1 | KEAP1 | Homo sapiens | Q14145 | 31262713 | |
|
Intra
|
NIBAN2 | Q96TA1 | KEAP1 | Homo sapiens | Q14145 | 31262713 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
NIBAN2 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P811690 | FAM129B Antibody (YA10161) | WB, IHC-P, IP, FC, ICC/IF | Human Mouse |