ZNF140 - zinc finger protein 140 Gene

Also Known as pHZ-39

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7699

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 3.0), testis (RPKM 2.6) and 25 other tissues.

ZNF140 Products (4)

mRNA Protein Name
NM_001300776.2 NP_001287705.1 zinc finger protein 140 isoform 2
NM_001300777.2 NP_001287706.1 zinc finger protein 140 isoform 3
NM_001300778.2 NP_001287707.1 zinc finger protein 140 isoform 2
NM_003440.4 NP_003431.2 zinc finger protein 140 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11470777 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7649249 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF140 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF140 P52738 CABP2 Homo sapiens Q9NPB3
Validated Y2H
32296183
Intra
ZNF140 P52738 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
ZNF140 P52738 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ZNF140 P52738 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ZNF140 P52738 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16097 ZNF10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16101 ZNF141 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16102 ZNF142 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16103 ZNF143 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16104 ZNF148 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16138 ZNF410 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16171 ZNF740 Human Pre-designed siRNA Set A Pre-designed Set / Unkown