GSPT1 degrader-26
GSPT1 degrader-26 is a molecular glue degrader containing an oxime structure that recruits the E3 ligase cereblon (CRBN). GSPT1 degrader-26 exerts antiproliferative activity against acute myeloid leukemia (AML) cells by inducing ubiquitination and proteasomal degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 degrader-26 can be used for research on GSPT1-related tumors.
For research use only. We do not sell to patients.
- CAS No.: 3065850-89-4
- Formula: C24H24N4O5
- Molecular Weight:448.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3065850-89-4
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Molecular Weight 448.47
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Formula C24H24N4O5
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SMILES
O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)/C(CC4=CC=CC=C4)=N/OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSPT1 degrader-26 Related Classifications
HY-190235 Related Classifications
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