HOOC-PEG2000-COOH
Based on 1 Customer Validation
HOOC-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and calcium ion chelator. HOOC-PEG2000-COOH inhibits platelet aggregation and contraction while promoting fibrinolysis and blood clot dissolution. HOOC-PEG2000-COOH can serve as a coating for superparamagnetic iron oxide nanoparticles in nanovaccine formulations, and as a bifunctional linker in pH-sensitive conjugates for siRNA delivery liposomes. HOOC-PEG2000-COOH can be used in research on thrombosis and atherosclerosis.
For research use only. We do not sell to patients.
- Purity : 99.91%
- CAS No.: 39927-08-7
- Molecular Weight:2000 (Average)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-W110542L
Poly(ethylene glycol) diacrylate (MW 3500)Polyethylene Glycol Derivative -
HY-W110542G
Poly(ethylene glycol) diacrylate (MW 6000)Polyethylene Glycol Derivative -
HY-W110542J
Poly(ethylene glycol) diacrylate (MW 700)Polyethylene Glycol Derivative -
HY-W110542O
Poly(ethylene glycol) diacrylate (MW 575),MEHQ as inhibitorPolyethylene Glycol Derivative -
HY-W110542N
Poly(ethylene glycol) diacrylate (MW 250),MEHQ as inhibitorPolyethylene Glycol Derivative -
HY-W110542P
Poly(ethylene glycol) diacrylate (MW 4000), MEHQ as inhibitorPolyethylene Glycol Derivative -
HY-W110542D
Poly(ethylene glycol) diacrylate (MW 1000)Polyethylene Glycol Derivative -
HY-Y0873
PEG300Neutral Polymer -
HY-Y0873A
PEG400 -
HY-Y0873J
PEG8000Biochemical reagent -
HY-W110542M
Poly(ethylene glycol) diacrylate (MW 20000)Polyethylene Glycol Derivative -
HY-W110542H
Poly(ethylene glycol) diacrylate (MW 10000)Polyethylene Glycol Derivative
Biological Activity
Description
In Vitro
HOOC-PEG2000-COOH affects coagulation initiation and reduces the maximum strength of the fibrin clot, with a coagulation index of -2.1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 39927-08-7
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Appearance Solid
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Molecular Weight 2000 (Average)
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Color White to off-white
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SMILES
O=C(O)COCCOCC(O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bian Y, et al. Carboxyl PEGylation of magnetic nanoparticles as antithrombotic and thrombolytic agents by calcium binding. Journal of colloid and interface science. 2023 May 15;638:672-685. [Content Brief]
[2]. Zhang L, et al. A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models. Nature communications. 2025 Mar 02;16(1):2111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HOOC-PEG2000-COOH Related Classifications
HY-174358A Related Classifications
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Keywords
- HOOC-PEG2000-COOH
- 39927-08-7
- Biochemical Assay Reagents
- Liposome
- superparamagnetic iron oxide nanoparticles
- thrombosis
- rat carotid artery thrombosis model
- fibrinolysis
- atherosclerosis
- extrinsic coagulation pathway
- siRNA delivery liposomes
- intrinsic coagulation pathway
- nanovaccine
- platelet aggregation
- Inhibitor
- inhibitor
- inhibit