IKZF2 degrader-11
IKZF2 degrader-11 is an isoindolinone-based CRBN molecular glue degrader containing a tetrahydropyran substituent that recruits CRL4CRBN to ubiquitinate and efficiently degrade IKZF2 (EC50 = 3 nM, Dmax = 97%). IKZF2 degrader-11 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2988110-08-1
- Formula: C23H30FN3O4
- Molecular Weight:431.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IKZF2 3 nM (EC50) |
IKZF1 > 1 μM (EC50) |
In Vitro
Chemical Information
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CAS No. 2988110-08-1
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Molecular Weight 431.50
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Formula C23H30FN3O4
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SMILES
CCC(N[C@H]1CCCO[C@@H]1CC2=C(F)C3=C(C(N(C4CCC(NC4=O)=O)C3)=O)C=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IKZF2 degrader-11 Related Classifications
HY-190209 Related Classifications
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