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Iscalimab (WT IgG1)

(Synonyms: CFZ-533 (WT IgG1); OM11-62MF (WT IgG1))
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Based on 1 Customer Validation

Iscalimab (WT IgG1) (CFZ-533 (WT IgG1)) is an IgG1 monoclonal antibody that retains a native wild-type Fc region and targets CD40. Iscalimab (WT IgG1) can be used in research concerning Graves' hyperthyroidism and autoimmune diseases.

For research use only. We do not sell to patients.

  • Purity : 99.64%
  • CAS No.: 2031153-61-2
  • Molecular Weight:146.08 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Iscalimab (WT IgG1)
  • Experimental Validation Results for Iscalimab (WT IgG1)
  • Experimental Validation Results for Iscalimab (WT IgG1)
  • Iscalimab (WT IgG1) Chemical Structure
    Iscalimab (WT IgG1) Chemical Structure
CAS No.: 2031153-61-2
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Iscalimab (WT IgG1) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All TNF Receptor Isoforms

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD40 Protein, Human can bind Iscalimab. The EC50 for this effect is 7.761 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling TNFRSF5/CD40 (red) with Iscalimab (anti-TNFRSF5/CD40) (HY-P99670). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Iscalimab (WT IgG1) Chemical Structure
    1/16
  • Iscalimab (WT IgG1)
  • Immobilized CD40 Protein, Human can bind Iscalimab. The EC50 for this effect is 7.761 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling TNFRSF5/CD40 (red) with Iscalimab (anti-TNFRSF5/CD40) (HY-P99670). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.