Isoxazole (Standard)
Isoxazole (Standard) is the analytical standard of Isoxazole (HY-W010649). This product is intended for research and analytical applications. Isoxazole is a member of the five-membered heterocycle drug scaffold. Isoxazole has been used as a BET bromodomain inhibitor and can improve β-cell function in a diabetic mouse model. Isoxazole and its derivatives exhibit broad biological activities (such as antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, anti-tuberculosis, and anti-diabetic effects). For example, the bicyclic Isoxazole can act as an HSP90 inhibitor, and the tricyclic Isoxazole is promising as a selective multidrug resistance protein (MRP1) inhibitor?.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 288-14-2
- Formula: C3H3NO
- Molecular Weight:69.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-W010649
IsoxazoleDrug Scaffold -
HY-B0322
SulfamethoxazoleSulfonamide Antibiotic -
HY-W010434
Leflunomide impurity 4Drug Impurity -
HY-B0322R
Sulfamethoxazole (Standard)Standard of Sulfamethoxazole -
HY-W010434R
5-Methylisoxazole-4-carboxylic acid (Standard) -
HY-W041676
5-Methylisoxazol-3-amineBiochemical Reagent -
HY-W103317
1,2-BenzisoxazoleAldehyde Oxidase Substrate -
HY-B0322B
Sulfamethoxazole 1000 µg/mL in methanolSulfonamide Antibiotic -
HY-W032938
COX-1-IN-4COX-1 Inhibitor -
HY-W007329
Isoxazol-3-amineBiochemical Reagent -
HY-34631
OxazoleBiochemical Reagent -
HY-69155
Oxazole-4-carboxylic acidMetal-organic Framework
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 288-14-2
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Molecular Weight 69.06
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Formula C3H3NO
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SMILES
C1=CON=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhu J, et al. The recent progress of isoxazole in medicinal chemistry. Bioorg Med Chem. 2018 Jul 23;26(12):3065-3075. [Content Brief]
[2]. Sysak A, et al. Isoxazole ring as a useful scaffold in a search for new therapeutic agents. Eur J Med Chem. 2017 Sep 8;137:292-309. [Content Brief]
[3]. Norman BH, et al. Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1)[J]. Bioorg Med Chem Lett. 2002 Mar 25;12(6):883-6. [Content Brief]
[4]. Agrawal N, Mishra P. The synthetic and therapeutic expedition of isoxazole and its analogs[J]. Med Chem Res. 2018;27(5):1309-1344. [Content Brief]
[5]. Kalwat MA, et al. Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells. ACS Chem Biol. 2016 Apr 15;11(4):1128-36. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Isoxazole (Standard) Related Classifications
HY-W010649R Related Classifications
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