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Cat. No.: HY-N22048

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Lysophosphatidylethanolamine (20:5)

Name: Lysophosphatidylethanolamine (20:5)
Brand: MedChemExpress
SKU: HY-N22048
Availability: PreOrder

(Synonyms: LysoPE(0:0/20:5))

Lysophosphatidylethanolamine (20:5) (LysoPE (0:0/20:5)) is a lysophosphatidylethanolamine containing a 20:5 acyl chain. Lysophosphatidylethanolamine (20:5) competitively binds to site 1 and site 2 of human serum albumin (HSA), with K_i values of 13.77 μM and 4.02 μM, respectively. Lysophosphatidylethanolamine (20:5) is elevated in Doxorubicin hydrochloride (HY-15142)-induced cardiotoxicity and is reduced by BP1. Lysophosphatidylethanolamine (20:5) is useful for metabolomics and biomarker studies of cardiomyopathy, type 2 diabetes insulin resistance, and obesity.

For research use only. We do not sell to patients.

CAS No.: 1354722-74-9
Formula: C₂₅H₄₂NO₇P
Molecular Weight:499.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lysophosphatidylethanolamine (20:5) Chemical Structure

CAS No.: 1354722-74-9

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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

Lysophosphatidylethanolamine (20:5) (LysoPE (0:0/20:5)) (3-5 μM; 30 min) binds to human serum albumin site 1 with a K_i of 13.77 μM and to site 2 with a K_i of 4.02 μM in a fluorescence displacement assay^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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Chemical Information

CAS No. 1354722-74-9
Molecular Weight 499.58
Formula C₂₅H₄₂NO₇P
SMILES

[H][C@@](COC(CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)(COP(O)(OCCN)=O)O
Synonyms

LysoPE(0:0/20:5)
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Thakur S, et al. Multiomics Analysis Reveals the Protective Effect of a Novel Bioactive Peptide (BP1) in Cardiomyopathy Using a Zebrafish Model. Journal of proteome research. 2026 May 01;25(5):2279-2295.

[2]. Diamanti K, et al. Integration of whole-body [F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes. Scientific reports. 2020 May 20;10(1):8343.

[3]. Inoue N, et al. Profiling of lysophosphatidylethanolamine molecular species in human serum and in silico prediction of the binding site on albumin. BioFactors (Oxford, England). 2022 Sep;48(5):1076-1088.

[4]. Kim HY, et al. Lysophospholipid profile in serum and liver by high-fat diet and tumor induction in obesity-resistant BALB/c mice. Nutrition (Burbank, Los Angeles County, Calif.). 2014;30(11-12):1433-41.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Lysophosphatidylethanolamine (20:5)

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Lysophosphatidylethanolamine (20:5)

All Endogenous Metabolite Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Lysophosphatidylethanolamine (20:5) Related Classifications

HY-N22048 Related Classifications

Bioz

Keywords

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