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Cat. No.: HY-P990654

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Radretumab

Name: Radretumab
Brand: MedChemExpress
SKU: HY-P990654
Price: 380.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

Radretumab is a human antibody used for imaging and radioimmunotherapy. Radretumab binds with high affinity to the oncofetal ED-B fibronectin isoform in tumor blood vessels and the extracellular matrix, preferentially localizing to tumor blood vessels without affecting normal tissues. Radretumab can be used in research on brain metastases of solid cancers, teratocarcinoma, and relapsed hematologic malignancies.

For research use only. We do not sell to patients.

Purity : 98.56%
CAS No.: 1253180-81-2
Molecular Weight:144.20 kDa

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Radretumab Chemical Structure

CAS No.: 1253180-81-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

In Vivo

Anti-cancer

Radretumab shows a good remission effect in teratocarcinoma tumor-bearing mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Gene ID

2335 [NCBI]

Accession

P02751

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa

Application

ELISA, FACS, Functional assay

Chemical Information

CAS No. 1253180-81-2
Appearance Liquid
Molecular Weight 144.20 kDa
Color Colorless to light yellow
Shipping

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

References

[1]. Poli GL, et al. Radretumab radioimmunotherapy in patients with brain metastasis: a 124I-L19SIP dosimetric PET study. Cancer immunology research. 2013 Aug;1(2):134-43.

[2]. Tsai WK, et al. Aligning physics and physiology: Engineering antibodies for radionuclide delivery. J Labelled Comp Radiopharm. 2018 Jul;61(9):693-714.

[3]. Erba PA, et al. Radioimmunotherapy with radretumab in patients with relapsed hematologic malignancies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012 Jun;53(6):922-7.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
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Purity:
Quantity:

Radretumab

Cell-ATP Viability Detection Kit

Bradford Protein Assay Kit

HOLO Human Interleukin-2 (IL-2) Detection Kit

Protein A Agarose

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

DPBS Buffer (1×)