Urease-IN-1

Cat. No.: HY-141806

CAS No.: 2719841-54-8

Target:

Bacterial

Research Areas:

Infection

Urease-IN-1 is an urease inhibitor with an IC₅₀ value of 2.21 ± 0.45 µM.

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Urease-IN-22

Cat. No.: HY-175644

Target:

Urease

Research Areas:

Others

Urease-IN-22 (Compound 9L) is a Urease inhibitor with an IC₅₀ of 0.15  μM. Urease-IN-22 is a piperazine-based derivative of Benzimidazole (HY-Y1825) .

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Urease-IN-10

Cat. No.: HY-149775

CAS No.: 1012205-70-7

Target:

Bacterial Urease

Research Areas:

Infection

Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC₅₀ of 3.59±0.07 μM and a K_i of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner .

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Urease-IN-13

Cat. No.: HY-163404

CAS No.: 3034860-91-5

Target:

Bacterial

Research Areas:

Infection Inflammation/Immunology

Urease-IN-13 (compound d8) is an inhibitor of urease with an IC₅₀ value of 1.21 μM. Urease-IN-13 can be used in the study of infectious gastritis and gastric ulcer .

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Urease-IN-19

Cat. No.: HY-168434

Target:

Urease

Research Areas:

Metabolic Disease

Urease-IN-19 (Compound 3c) is a potent urease inhibitor with an IC₅₀ value of 2.7 µM. Urease-IN-19 is promising for research of kidney stones and stomach ulcers .

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Urease-IN-9

Cat. No.: HY-156369

Target:

Bacterial

Research Areas:

Infection

Urease-IN-9 (Compound 1e) is an urease inhibitor (IC₅₀: 19.5?μM) .

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Urease-IN-5

Cat. No.: HY-152669

Target:

Bacterial

Research Areas:

Infection

Urease-IN-5 is an inhibitor of urease with an IC₅₀ value of 1.473 µM. Urease-IN-5 has low cytotoxicity and inhibitory activity on P. vulgaris with an IC₅₀ value of 17.78 µg/mL .

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Urease-IN-7

Cat. No.: HY-155970

CAS No.: 1129406-54-7

Target:

Bacterial

Research Areas:

Infection Inflammation/Immunology

Urease-IN-7 (Compound 5k) is a competitive Urease inhibitor (IC₅₀: 3.33 μM, K_i: 3.62 μM). Urease-IN-7 can be used for research of peptic and gastric ulcers .

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Urease-IN-8

Cat. No.: HY-155973

CAS No.: 517906-16-0

Target:

Bacterial

Research Areas:

Infection Inflammation/Immunology

Urease-IN-8 (Compound 5e) is a competitive Urease inhibitor (IC₅₀: 3.51 μM, K_i: 3.11 μM). Urease-IN-8 can be used for research of peptic and gastric ulcers .

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Urease-IN-20

Cat. No.: HY-170937

CAS No.: 2998940-98-8

Target:

Bacterial Apoptosis Reactive Oxygen Species (ROS)

Research Areas:

Infection

Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori). Urease-IN-20 inhibits H. pylori with an IC₅₀ of 0.14 μM. Urease-IN-20 reduces cell Apoptosis and decreases ROS and γH2AX in GES-1 cells infected with H. pylori. Urease-IN-20 exhibits significant gastric mucosal protective effects. Urease-IN-20 shows the potential for H. pylori research .

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Urease-IN-15

Cat. No.: HY-161761

Target:

Bacterial

Research Areas:

Infection

Urease-IN-15 (compound 5g) is an uncompetitive inhibitor of urease in manner with the IC₅₀ of 3.80 µM .

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Urease-IN-4

Cat. No.: HY-152668

Target:

Bacterial

Research Areas:

Infection

Urease-IN-4 is an effective inhibitor of urease with an IC₅₀ value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC₅₀ value of 15.27 µg/mL .

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Urease-IN-21

Cat. No.: HY-175169

Target:

Bacterial Urease

Research Areas:

Infection

Urease-IN-21 (Compound 11b) is a Urease inhibitor with an IC₅₀ of 0.12  μM. Urease-IN-21 has potent antibacterial activity against helicobacter pylori (H. pylori) and inhibitor activity against P450 enzyme (CYP2C19, CYP2C9, and CYP3A4). Urease-IN-21 can be used for H. pylori infection research .

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Urease-IN-12

Cat. No.: HY-162149

CAS No.: 1047677-17-7

Target:

Bacterial

Research Areas:

Infection

Urease-IN-12 (compound 5e) is a competitive urease inhibitor (IC₅₀: 0.35 μM) with the potential to inhibit gastritis and peptic ulcer caused by Helicobacter pylori .

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