4 Results for "

2-Iodoadenosine

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "2-Iodoadenosine" in MCE Product Catalog:

Cat. No.: HY-W008552
CAS No.: 35109-88-7
2-Iodoadenosine is an activator of the A2A receptor (A2AR), with a human target EC50 of 5.4 µM. 2-Iodoadenosine stimulates cAMP production through adenosine A2A receptors. 2-Iodoadenosine inhibits Forskolin (HY-1537)-stimulated cAMP production through adenosine A3 receptors. 2-Iodoadenosine exhibits competitive inhibition of GI-nucleoside hydrolase relative to guanosine, with a Km/Ki of 61. Research related to central nervous system diseases, cancer, and cardiovascular diseases [2].
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Cat. No.: HY-154114
CAS No.: 118706-49-3
Research Areas:  

Cancer

2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-P3567
CAS No.: 159600-82-5
Target:  

Melanocortin Receptor

Research Areas:  

Neurological Disease

(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .
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Cat. No.: HY-P2434
CAS No.: 846569-60-6
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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