481 Results for "

2A13

" in MedChemExpress (MCE) Product Catalog:
Products (481)

481 Results for "2A13" in MCE Product Catalog:

45
GSK-690693
GSK-690693
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45 Publications Verification
Cat. No.: HY-10249
CAS No.: 937174-76-0
Purity:  98.47%
Target:  

Akt AMPK Autophagy

Research Areas:  

Cancer

GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
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4
CTS-1027
CTS-1027
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4 Cited Publications
Cat. No.: HY-10398
CAS No.: 193022-04-7
Purity:  99.24%
Synonyms: Ro 1130830; RS 130830
Target:  

MMP

Research Areas:  

Cancer

CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1.
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4
PPTN hydrochloride
PPTN hydrochloride
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4 Cited Publications
Cat. No.: HY-110322
CAS No.: 1992047-65-0
Purity:  99.89%
Target:  

P2Y Receptor

Research Areas:  

Inflammation/Immunology

PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity .
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4
PPTN
PPTN
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4 Cited Publications
Cat. No.: HY-110322A
CAS No.: 1160271-30-6
Purity:  99.63%
Target:  

P2Y Receptor

Research Areas:  

Inflammation/Immunology

PPTN, a chemical probe, is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity .
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4
IDH1 Inhibitor 2
IDH1 Inhibitor 2
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4 Cited Publications
Cat. No.: HY-128661
CAS No.: 2244895-42-7
Purity:  99.40%
Target:  

Isocitrate Dehydrogenase (IDH)

Research Areas:  

Metabolic Disease

IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development .
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4
Timapiprant
Timapiprant
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4 Cited Publications
Cat. No.: HY-15342
CAS No.: 851723-84-7
Purity:  99.48%
Synonyms: OC000459
Target:  

Prostaglandin Receptor

Research Areas:  

Inflammation/Immunology Endocrinology

Timapiprant (OC000459) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant (OC000459) potently displaces [ 3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant (OC000459) inhibits mast cell activation of Th2 lymphocytes and eosinophils .
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4
Timapiprant sodium
Timapiprant sodium
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4 Cited Publications
Cat. No.: HY-15342A
CAS No.: 950688-14-9
Purity:  98.71%
Synonyms: OC000459 sodium
Target:  

Prostaglandin Receptor

Research Areas:  

Inflammation/Immunology Endocrinology

Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [ 3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils .
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3
Abemaciclib metabolite M2
Abemaciclib metabolite M2
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3 Cited Publications
Cat. No.: HY-128669
CAS No.: 1231930-57-6
Purity:  99.75%
Synonyms: LSN2839567
Target:  

CDK Drug Metabolite

Research Areas:  

Cancer

Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity .
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3
TG 100572 Hydrochloride
TG 100572 Hydrochloride
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3 Cited Publications
Cat. No.: HY-10185
CAS No.: 867331-64-4
Purity:  98.96%
Target:  

Src VEGFR FGFR PDGFR

Research Areas:  

Inflammation/Immunology

TG 100572 Hydrochloride is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.
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3
Cotinine
Cotinine
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3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Category:  

Alkaloids Pyrrole Alkaloids 500 - Internal Server Error | MedChemExpress

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