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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
8-Bromo-Cyclic ADP-Ribose
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "8-Bromo-Cyclic ADP-Ribose" in MCE Product Catalog:
Cat. No.: HY-117804
CAS No.: 151898-26-9
Synonyms: 8-Bromo-Cyclic ADP-Ribose
Target:
Research Areas:
8-Br-cADPR (8-Bromo-Cyclic ADP-Ribose) is a membrane-permeable competitive antagonist of Cyclic ADP-ribose (cADPR) (HY-N7395) and an antagonist of TRPM2 ion channels. 8-Br-cADPR blocks cADPR-dependent RyR, SR calcium mobilization, and cADPR-mediated signaling; reduces Paclitaxel (HY-B0015)-induced axonal calcium flux, and protects against Paclitaxel-induced axonal degeneration/peripheral neuropathy. 8-Br-cADPR blocks isoproterenol-induced pulmonary artery dilation, angiotensin II-induced arterial calcium signaling/contraction, and hypoxic pulmonary vasoconstriction. 8-Br-cADPR can be used in research related to neurological diseases and cancer .
Cat. No.: HY-175081
Synonyms: 8-Bromo-Cyclic ADP-Ribose sodium salt
Target:
Research Areas:
8-Br-cADPR sodium salt (8-Bromo-Cyclic ADP-Ribose sodium salt) is a membrane-permeable competitive antagonist of Cyclic ADP-ribose (cADPR) (HY-N7395) and an antagonist of TRPM2 ion channels. 8-Br-cADPR sodium salt blocks cADPR-dependent RyR, SR calcium mobilization, and cADPR-mediated signaling; reduces Paclitaxel (HY-B0015)-induced axonal calcium flux, and protects against Paclitaxel-induced axonal degeneration/peripheral neuropathy. 8-Br-cADPR sodium salt blocks isoproterenol-induced pulmonary artery dilation, angiotensin II-induced arterial calcium signaling/contraction, and hypoxic pulmonary vasoconstriction. 8-Br-cADPR sodium salt can be used in research related to neurological diseases and cancer .
Cat. No.: HY-134269A
Synonyms: 7-deaza-8-Bromo-cADPR disodium; 7-deaza-8-Bromo-Cyclic ADP Ribose disodium
Target:
Research Areas:
8-Br-7-CH-cADPR disodium (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. 8-Br-7-CH-cADPR disodium shows partial inhibition of calcium elevation caused by sTIR dimerization. 8-Br-7-CH-cADPR disodium significantly decreases Paclitaxel (HY-B0015)-induced axon degeneration .
Cat. No.: HY-134269
CAS No.: 189876-06-0
Synonyms: 7-Deaza-8-Bromo-cADPR; 7-Deaza-8-Bromo-Cyclic ADP Ribose
Target:
Research Areas:
8-Br-7-CH-cADPR (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. 8-Br-7-CH-cADPR shows partial inhibition of calcium elevation caused by sTIR dimerization. 8-Br-7-CH-cADPR significantly decreases Paclitaxel (HY-B0015)-induced axon degeneration .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
