1 Result for "

AAB001

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "AAB001" in MCE Product Catalog:

Cat. No.: HY-P99185
CAS No.: 648895-38-9
Synonyms: AAB-001
Research Areas:  

Neurological Disease

Bapineuzumab (AAB-001) is a humanized IgG1 monoclonal antibody that binds to the N-terminal region of amyloid beta in a helical conformation. Bapineuzumab induces microglial activation by upregulating CD11B, producing pro-inflammatory cytokines (IL-1β and TNFα), clearing plaques, and reducing insoluble and aggregated Aβ. Bapineuzumab can be used for research on Alzheimer's disease .
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