2 Results for "

AG205

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AG205" in MCE Product Catalog:

Cat. No.: HY-115625
CAS No.: 1375078-57-1
Research Areas:  

Cancer

AG-205 is a progesterone receptor membrane component 1 (PGRMC1) antagonist and CGT inhibitor, with an IC50 of 50 μM against rat CGT. AG-205 exhibits antimitotic, antimigratory and anti-invasive activities. AG-205 increases the expression of genes encoding cholesterol biosynthesis pathway or steroidogenic enzymes. AG-205 promotes the regulation of cell cycle by apoptosis and reduces the migratory and invasive capacities of ovarian and breast cancer cells. AG-205 can be used in research related to renal cancer and breast cancer .
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Cat. No.: HY-121012
CAS No.: 442656-02-2
Target:  

Drug Isomer

Research Areas:  

Others

(rac)-AG-205 is an isomer of AG-205 (HY-115625). AG-205 is an antagonist of progesterone receptor membrane component 1 (PGRMC1) and an inhibitor of ceramide galactosyltransferase (CGT); it can be used in research related to renal cancer and breast cancer. .
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