1 Result for "

AX202

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AX202" in MCE Product Catalog:

Cat. No.: HY-P991363
Target:  

Myosin STAT

Research Areas:  

Inflammation/Immunology

AX-202 is a humanized anti-S100A4 monoclonal antibody that neutralizes S100A4. AX-202 blocks downstream profibrotic and proinflammatory effects. AX-202 exerts antifibrotic effects in skin fibrosis. AX-202 induces regression of pre-established skin fibrosis. AX-202 modulates anti-inflammatory and antifibrotic transcriptional pathways. AX-202 inhibits STAT3 phosphorylation. AX-202 induces AMPK and CASQ1 expression. AX-202 modulates SSc-related transcriptional signatures. AX-202 reduces tenascin-C, a DAMP and endogenous TLR4 ligand. AX-202 can be used for the research of systemic sclerosis .
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