2 Results for "

Alfadolone

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Alfadolone" in MCE Product Catalog:

Cat. No.: HY-108068
CAS No.: 23930-37-2
Purity:  98.50%
Synonyms: Alfadolone acetate; GR 2/1574
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Alphadolone acetate (Alfadolone acetate) is a steroid agent that can suppress or relieve pain, with antinociception .
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Cat. No.: HY-117979
CAS No.: 14107-37-0
Synonyms: Alfadolone
Target:  

GABA Receptor Fungal

Research Areas:  

Infection Neurological Disease

Alphadolone (Alfadolone) is a GABAA positive allosteric modulator with antinociceptive activity. Alphadolone produces GABAA-mediated antinociception and analgesia, and can induce anesthesia, loss of righting reflex, and deep sedation. Alphadolone blocks calcium channels and downstream cascades of calcium influx, and inhibits histamine release from mast cells. Alphadolone enhances the antinociceptive effects of opioids. Alphadolone promotes Candida albicans yeast/hyphal growth, increases lipid and oxygen uptake, alters sterol composition, and enhances tolerance to polyene antifungals . Alphadolone can be used in pain-related research .
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