75 Results for "

Angina pectoris

" in MedChemExpress (MCE) Product Catalog:
Products (75)

75 Results for "Angina pectoris" in MCE Product Catalog:

55
Propranolol hydrochloride
Propranolol hydrochloride
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55 Publications Verification
Cat. No.: HY-B0573
CAS No.: 318-98-9
Category:  

Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Adrenergic Receptor Bacterial

Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [ 3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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55
Propranolol
Propranolol
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55 Publications Verification
Cat. No.: HY-B0573B
CAS No.: 525-66-6
Category:  

Cardiovascular Disease Alkaloids Natural Products Neurological Disease Other Alkaloids Plants Aconitum carmichaeli Debx. Extract Disease Research Fields Ranunculaceae Extract

Target:  

Adrenergic Receptor Bacterial

Propranolol is a nonselective and BBB-permeable β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol inhibits [ 3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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21
Atenolol
Atenolol
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21 Cited Publications
Cat. No.: HY-17498
CAS No.: 29122-68-7
Synonyms: (RS)-Atenolol
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease Neurological Disease Endocrinology Cancer

Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris .
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11
Diltiazem
Diltiazem
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11 Cited Publications
Cat. No.: HY-B0632
CAS No.: 42399-41-7
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease Cancer

Diltiazem is an orally active L-type Ca 2+ channel blocker. Diltiazem shows antihypertensive and antiarrhythmic effects. Diltiazem can be used for the research of cardiac arrhythmia, hypertension, and angina pectoris .
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6
(S)-Timolol maleate
(S)-Timolol maleate
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6 Cited Publications
Cat. No.: HY-17380
CAS No.: 26921-17-5
Synonyms: (S)-L-714,465 maleate; MK 950
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease Neurological Disease Cancer

(S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction .
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5
Nadolol
Nadolol
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5 Cited Publications
Cat. No.: HY-B0804
CAS No.: 42200-33-9
Synonyms: SQ-11725
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research .
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5
Isosorbide mononitrate
Isosorbide mononitrate
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5 Cited Publications
Cat. No.: HY-B0642
CAS No.: 16051-77-7
Synonyms: Isosorbide-5-mononitrate
Category:  

Cardiovascular Disease Disease Research Fields Cancer

Target:  

Autophagy Apoptosis

Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart failure and coronary heart disease .
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3
Acebutolol hydrochloride
Acebutolol hydrochloride
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3 Cited Publications
Cat. No.: HY-17497A
CAS No.: 34381-68-5
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease Endocrinology

Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias .
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3
Acebutolol
Acebutolol
0 Images
3 Cited Publications
Cat. No.: HY-17497
CAS No.: 37517-30-9
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research .
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2
Griseofulvin
Griseofulvin
0 Images
2 Cited Publications
Cat. No.: HY-17583
CAS No.: 126-07-8
Category:  

Natural Products Microorganisms Disease Research Fields Cancer

Target:  

Environmental Pollutants Antibiotic Apoptosis Fungal Endogenous Metabolite Bcl-2 Family Caspase Microtubule/Tubulin

Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome .
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1
Molsidomine
Molsidomine
0 Images
1 Cited Publications
Cat. No.: HY-B1069
CAS No.: 25717-80-0
Synonyms: SIN-10; Morsydomine
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease Neurological Disease Metabolic Disease

Molsidomine, a nitric oxide (NO) donor, is an orally active vasodilator agent. Molsidomine is a prodrug that can be rapidly metabolized in the liver to its active metabolite, Linsidomine (HY-101200). Molsidomine can be used for the study of angina pectoris, mental disorders and diabetic complications .
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Bevantolol hydrochloride
Bevantolol hydrochloride
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Cat. No.: HY-121186
CAS No.: 42864-78-8
Purity:  98.98%
Synonyms: SOM3355
Target:  

Adrenergic Receptor Monoamine Transporter

Bevantolol hydrochloride (SOM3355) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol hydrochloride blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol hydrochloride reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol hydrochloride is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease .
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Propranolol-d7 (ring-d7)
Propranolol-d7 (ring-d7)
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Cat. No.: HY-B0573S1
CAS No.: 344298-99-3
Propranolol-d7 (ring-d7) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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Atenolol-d7
Atenolol-d7
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Cat. No.: HY-17498S
CAS No.: 1202864-50-3
Synonyms: (RS)-Atenolol-d7
Atenolol-d7 is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris .
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Pranidipine
Pranidipine
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Cat. No.: HY-19664
CAS No.: 99522-79-9
Synonyms: OPC-13340
Target:  

Calcium Channel NO Synthase

Research Areas:  

Cardiovascular Disease

Pranidipine (OPC-13340) is an orally active L-type voltage-dependent calcium channel (L-VDCC) blocker with a Ki value of 0.16 nM. Pranidipine inhibits calcium-induced contraction, suppresses slow-response action potentials, shortens action potential duration, reduces systolic and diastolic blood pressure, and exerts vasodilatory effects. Pranidipine enhances its vasodilatory effect by blocking NO decomposition. Pranidipine can be used in research related to essential hypertension, angina pectoris, myocardial infarction, and dilated cardiomyopathy .
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Propranolol-d7
Propranolol-d7
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Cat. No.: HY-B0573BS
CAS No.: 98897-23-5
Propranolol-d7 is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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Propranolol-d7 hydrochloride
Propranolol-d7 hydrochloride
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Cat. No.: HY-B0573S
CAS No.: 1613439-56-7
Propranolol-d7 (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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Prenylamine
Prenylamine
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Cat. No.: HY-A0257
CAS No.: 390-64-7
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Prenylamine is a calcium channel blocker of the amphetamine chemical class. Prenylamine can be used as a vasodilator and can be used for the research of angina pectoris .
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YS-201
YS-201
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Cat. No.: HY-U00137
CAS No.: 108852-42-2
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

YS-201 is a dihydropyridine-type calcium channel antagonist. YS-201 has the potential for angina pectoris and hypertension treatment.
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Hydroxytanshinone IIA
Hydroxytanshinone IIA
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Cat. No.: HY-N7177
CAS No.: 18887-18-8
Category:  

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