60 Results for "

Anti-Tuberculosis agent

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "Anti-Tuberculosis agent" in MCE Product Catalog:

3
TBAJ-587
TBAJ-587
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3 Cited Publications
Cat. No.: HY-111747
CAS No.: 2252316-16-6
Purity:  95.07%
Target:  

Bacterial

Research Areas:  

Infection Cardiovascular Disease

TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization .
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1
Ftaxilide
Ftaxilide
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1 Cited Publications
Cat. No.: HY-B1040
CAS No.: 19368-18-4
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Ftaxilide is an anti-ulcer agent. Ftaxilide exhibits notable biological properties, including antibacterial, antioxidant, and anti-tuberculosis activities. Ftaxilide shows weak binding to the Mycobacterium tuberculosis target protein (PDB ID: 1GTV). Ftaxilide can be used in research on irritable bowel syndrome and tuberculosis .
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L-2-Aminobutyric acid
L-2-Aminobutyric acid
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Cat. No.: HY-W010589
CAS No.: 1492-24-6
Synonyms: H-Abu-OH
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Drug Intermediate

L-2-Aminobutyric acid (H-Abu-OH) is a non-proteinogenic amino acid that exists in human tissues and body fluids. L-2-Aminobutyric acid is formed by the transamination of oxobutyric acid. L-2-Aminobutyric acid can serve as a precursor for anticonvulsant and anti-tuberculosis agents and is a key intermediate in the chemical and pharmaceutical industries.
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TBI-166
TBI-166
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Cat. No.: HY-148564
CAS No.: 1353734-12-9
Purity:  98.00%
Target:  

Bacterial

Research Areas:  

Infection

TBI-166, a riminophenazine analogue, is an orally active anti-tuberculosis agent with fewer adverse reactions than the lead riminophenazine compound, Clofazimine (HY-B1046) .
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JFD01307SC
JFD01307SC
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Cat. No.: HY-W028047
CAS No.: 51070-56-5
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

JFD01307SC is a glutamine synthetase inhibitor and anti-tuberculosis agent. JFD01307SC acts as a mimic of L-Glutamate and thus target enzymes involved in glutamine biosynthesis .
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Sudoterb
Sudoterb
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Cat. No.: HY-14990
CAS No.: 676266-31-2
Purity:  98.38%
Synonyms: LL 3858
Target:  

Bacterial

Research Areas:  

Infection

Sudoterb (LL 3858) is an orally active anti-Tuberculosis agent .
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GSK2200150A
GSK2200150A
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Cat. No.: HY-112091
CAS No.: 1443138-53-1
Purity:  99.55%
Target:  

Bacterial

Research Areas:  

Infection

GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.
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(Rac)-TBAJ-876
(Rac)-TBAJ-876
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Cat. No.: HY-128866A
CAS No.: 2131784-39-7
Purity:  99.54%
Target:  

Bacterial

Research Areas:  

Infection

(Rac)-TBAJ-876 is a racemate of TBAJ-876. TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline (HY-14881). TBAJ-876 has the potential for the research of tuberculosis .
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Antituberculosis agent-16
Antituberculosis agent-16
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Cat. No.: HY-178436
Target:  

Bacterial

Research Areas:  

Infection

Antituberculosis agent-16 is an orally active antituberculosis agent. Antituberculosis agent-16 exhibits stable antituberculosis activity with a MIC of 0.48 μg/mL against Mycobacterium tuberculosis H37Rv sensitive strain and 0.49 μg/mL against multidrug-resistant strain 14862. Antituberculosis agent-16 shows high Caco-2 permeability. Antituberculosis agent-16 can be used for the research of infection .
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NITD-304
NITD-304
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Cat. No.: HY-W064918
CAS No.: 1473450-60-0
Target:  

Bacterial

Research Areas:  

Infection

NITD-304 is an orally active anti-tuberculosis agent. NITD-304 exerts inhibitory and bactericidal activities gainst Mycobacterium tuberculosis and multidrug-resistant Mycobacterium tuberculosis. NITD-304 inhibits mycobacterial cell wall biosynthesis and demonstrates synergistic or additive growth inhibitory activity with select antibacterial agents. NITD-304 shows low risk of cardiotoxicity and drug-drug interactions, with no inhibition of major cytochrome P-450 enzymes or hERG channel. NITD-304 can be used for the research of tuberculosis and multidrug-resistant tuberculosis .
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Antituberculosis agent-5
Antituberculosis agent-5
0 Images
Cat. No.: HY-151514
CAS No.: 313981-44-1
Purity:  99.76%
Target:  

Bacterial

Research Areas:  

Infection

Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL .
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Antituberculosis agent-8
Antituberculosis agent-8
0 Images
Cat. No.: HY-152138
CAS No.: 2874263-74-6
Target:  

Bacterial Fungal

Research Areas:  

Infection

Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM .
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Antituberculosis agent-2
Antituberculosis agent-2
0 Images
Cat. No.: HY-146057
CAS No.: 2411741-01-8
Target:  

Bacterial

Research Areas:  

Infection

Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against agent-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 μg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability .
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4-Piperidinecarboxamide
4-Piperidinecarboxamide
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Cat. No.: HY-142031
CAS No.: 519034-65-2
Target:  

Bacterial

Research Areas:  

Infection

4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor. 4-Piperidinecarboxamide is a promising anti-tuberculosis (TB) agent .
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Rifamdin
Rifamdin
0 Images
Cat. No.: HY-W738288
CAS No.: 89499-17-2
Target:  

Bacterial Drug Derivative DNA/RNA Synthesis

Research Areas:  

Infection

Rifamdin is a derivative of Rifampicin (HY-B0272). Rifamdin is an anti-tuberculosis agent. Rifamdin exerts its antibacterial effect by inhibiting the synthesis of bacterial RNA .
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Sophoradiol
Sophoradiol
0 Images
Cat. No.: HY-N11259
CAS No.: 6822-47-5
Category:  

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